Appetite. What are the molecules that control appetite? (hint: next sentence) How do the
orexins, leptin and ghrelin work together to control appetite? Which cells are responsible for
producing these molecules and what are the molecular pathways that are activated? Identify
the targets and how the signaling pathways are regulated. Which molecules oppose appetite
and how do they suppress the craving for food? You may need to consider not only the signaling
pathways but the neural pathways as well.
Creating a Discussion Outline
1. Once you have a list of facts, the next step is to put together an outline of your discussion.
2. Be sure to look at the question you are trying to answer. Frame your arguments (data/facts) in
an order that makes logical sense.
a. Look for holes and find more references
b. Move things around so that you tell an interesting story.
c. Check to see that you have a beginning, a middle, and an ending.
3. Once you are satisfied with the flow of the discussion, create an outline for submission and one
that you will actually use. See example:
a. Idea/assertion #1
i. Facts 1, 2, 3 etc. (list them though, I’m making this short)
1. Any sub-facts you already know you want to use., etc.
b. Idea/assertion #2
i. Facts 4, 5, 6 etc.
4. Create an outline for your discussion with the ideas and facts that you plan to use. Not only will
this speed up the process of writing the paper and help you organize and see your central thesis
and supporting evidence, it will also help you see the flow of your paper and help you see where
the strengths and weaknesses might be.
a. More detail is better, don’t just do the bare minimum. This is not busy work, but instead
trying to get you to think ahead to produce a strong paper.