Anthracycline antibiotics are very commonly used chemotherapeutic agents, and one of their most serious side effects is cardiac toxicity.

Topic of assignment

Anthracycline antibiotics are very commonly used chemotherapeutic agents, and one of their most serious side effects is cardiac toxicity. Describe the likely mechanism, any risk factors and an overview of how this toxicity may be prevented, focussing on the underlying pathophysiology and pharmacology.

 

 Assessment Criteria

Present your assignment using the following information as a guide. Please copy the question that you are answering and place this at the top of your assignment.

The maximum length of the assignment is 1000 words. For each 100 words that you exceed the word limit, you will be penalised 5% of your overall mark. For example, for an assignment that is 1200 words long, your assignment will be marked according to the criteria, and the overall mark will be reduced by 10%. The question and references will not count towards your word count.

Your assignment should include the following sections:
Background: An overview of the main issue that you are discussing, more specifically a brief background to the disease and/or the drug(s)/treatment that you are discussing. For example, you could provide a general overview of the disease and the treatment approach, including the mechanism of action of the drug/treatments that you are going to discuss in the remainder of your assignment. Approximate length 200 words.

Main Body: This will include a detailed discussion of the main question(s) within your selected assignment. Remember that this should focus on the underlying pharmacology and/or pathophysiology of the relevant disease and/or the drug(s)/treatment and specifically answer the primary question(s) – it should be in much more detail that was covered in the background. Approximate length 700 words

Overview/Conclusion: Based upon what you have written in previous sections, state the most important messages that you would like someone to have after reading your assignment. For example, can you provide a brief overview of your assignment and/or what is your conclusion from your assignment, is this a medication/treatment that should be used for the condition or what are the risks of using this medication/treatment. Approximate length 100 words

You will also be awarded marks for appropriate referencing, presentation, layout and design as described below. Referencing should be performed according to the UniSA Harvard referencing guidelines (information is available at http://i.unisa.edu.au/students/student-support- services/study-support/academic-integrity-and-referencing/).

Other information

Please follow the assignment criteria, and focus on the main points which are Pharmacology, pathophysiology. Anthracycline antibiotics drugs include Doxorubicin (the most common one), Daunorubicin, Epirubicin, Idarubicin, Mitoxantrone.

I have provided 8 references please use them and if you see others you can add them but not more 10 references and the reference guide line will provide as PDF file